Clinical Trials

Diabetes & Metabolic Diseases Clinical Trials

These are among the diabetes and metabolic-disease clinical trials currently open.

Title	Effect of renin inhibition on cardiovascular autonomic nerve function in diabetes (29011).
Purpose	The purpose of this research study is to test the effectiveness of a medication to improve nerve function.
Qualifications	Individuals 18 years and older with Type 1 or Type 2 diabetes.
Benefits	Free tests to measure nerve function. Payment to you of up to $200.
Contact	Raelene E. Maser, Ph.D., 302-623-3834.

Title	A Phase 2/3, randomized, double-blind, multicenter, multinational, 4-arm, controlled, dose-ranging study to evaluate efficacy and safety of MGA031, a humanized, FcR non-binding, anti-CD3 monoclonal antibody, in children and adults with recent-onset Type 1 diabetes mellitus (26227).
Purpose	The purpose of this study is to find out if an experimental drug called MGA031 (also called hOKT3gamma-1 [Ala-Ala]) improves control of sugar in the blood, decreases the need for insulin and is safe for people with Type 1 diabetes mellitus.
Qualifications	Have been diagnosed with Type 1 diabetes in the last 12 weeks. Are between 8 and 35 years of age.
Benefits	Physical examinations. Laboratory tests. Study medications. Reimbursement for time/travel expenses up to $1290.
Contact	Debbie Moore, 302-623-3838.